Diabetes is one of the most prevalent diseases in the world with more than 500 million people diagnosed with it worldwide. It claims more than 7 millions lives each year. The condition is characterized by high blood sugar levels. Therapy Solution for Diabetes: Scientists Have Revealed They made a response-immediate smart insulin in reaction to the variation of blood sugar. The study appeared in the journal Nature.
What is Diabetes and Development of New Insulin.
Types of Diabetes
- Type 1 Diabetes:Usually starts in childhood; little or no insulin made.
- Diabetes Type 2: Cells in the body develop resistance for insulin, making it impossible for pancreas to produce the required levels.
Implications of Diabetes
- Difficulty in administering insulin because of erratic blood glucose.
- Requirement of continuous checking and effective managing of insulin dosages
Issues with Insulin Management
- Systems in place now have store insulin and are released according to the changes existing in blood sugar, they do not respond to real-time changes.
Engineering a New Insulin
- NNC2215, a new insulin, has been developed by teams in Denmark, the UK and Czechia working with University of Bristol.
- NNC2215 consists of two major parts: a ring structure and a glucoside molecule.
- Will help diabetes patients with the challenges of managing blood sugars and improve their overall quality of life.
Testing and Development
- In rats and pigs, NNC2215 has been found to effectively lower blood glucose levels.
- Its swift activation and requirement for slow stimulation are some present challenges.
Future Directions
- Further development of NNC2215 is a prerequisite for the realization of a more convenient and safer mealtime insulin therapy.
Month: Current Affairs - November 14, 2024
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