IISc Launches Brain Co-Processor Moonshot Project to Advance Neuro-AI Rehabilitation

IISc and Pratiksha Trust Partner to Develop AI-Powered Brain Co-Processors

The Indian Institute of Science Bengaluru has launched a major “moonshot” research initiative to develop brain co-processors that combine neuromorphic hardware with artificial intelligence (AI) algorithms. The project is supported by the Pratiksha Trust, established by Kris Gopalakrishnan and Sudha Gopalakrishnan.

A memorandum of understanding formalising the collaboration was signed at IISc in the presence of senior researchers and institutional leaders. The initiative aims to create advanced neural technologies capable of decoding brain signals, processing them using AI and delivering corrective feedback to restore or enhance brain functions.

Concept of AI-Enabled Brain Co-Processors

Brain co-processors represent an emerging class of neurotechnology designed to assist or restore the brain’s natural capabilities. The IISc project seeks to develop both implantable and non-invasive devices that can record neural activity and interpret these signals using AI algorithms.

These devices will function as closed-loop systems , continuously analysing neural patterns and delivering corrective stimulation or neurofeedback to the brain. Such technology could help patients recover abilities such as coordinated movement, reaching and grasping by reinforcing correct neural pathways.

Focus on Stroke Rehabilitation

One of the primary goals of the project is to support rehabilitation for stroke survivors, particularly those affected by strokes involving the middle cerebral artery , which often lead to severe motor impairment.

In the first phase, researchers will develop a non-invasive neural co-processor capable of providing sensorimotor feedback to help patients perform goal-directed movements. At the same time, work will begin on an implantable version that can directly interact with brain regions responsible for movement and coordination.

The second phase will focus on creating a minimally invasive embedded co-processor intended to restore sensorimotor coordination in individuals with long-term neurological deficits.

Indigenous Neurotechnology Development

A key objective of the initiative is to strengthen India’s indigenous capabilities in neurotechnology and AI-driven healthcare . Researchers plan to design implant hardware, neuromorphic processors and AI software platforms within the country.

The project will also generate India-specific neural datasets , including stereo EEG and electrocorticography recordings, to train advanced AI models. Additionally, open-source AI tools, datasets and visualisation platforms will be released as digital public goods to encourage broader scientific collaboration.

Important Facts for Exams

• The Brain Co-Processors Moonshot Project has been launched by the Indian Institute of Science (IISc), Bengaluru .

• The project is funded by the Pratiksha Trust founded by Kris and Sudha Gopalakrishnan.

• Neuromorphic computing mimics the structure and functioning of the human brain.

• The technology aims to assist stroke rehabilitation by decoding and stimulating neural signals .

Collaborative Research and Clinical Validation

The initiative builds upon IISc’s Brain, Computation and Data Science programme , which involves more than 20 faculty members across multiple disciplines. Scientists from